Psychopharmacological treatment of social phobia: clinical and biochemical effects of brofaromine, a selective MAO-A inhibitor.

@article{Vliet1992PsychopharmacologicalTO,
  title={Psychopharmacological treatment of social phobia: clinical and biochemical effects of brofaromine, a selective MAO-A inhibitor.},
  author={Irene M van Vliet and Johan A. den Boer and Herman G. M. Westenberg},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={1992},
  volume={2 1},
  pages={21-9}
}
There is circumstantial evidence that antidepressants, particularly monoamine oxidase inhibitors (MAOIs) and beta-blockers, may have some beneficial effects in social phobia. In this study 30 patients with social phobia (DSM-IIIR) were treated with the selective and reversible MAO-A inhibitor brofaromine, using a 12-week double-blind placebo controlled design. A clinical relevant improvement was seen in 80% of the patients treated with brofaromine (150 mg daily). A significant improvement was… CONTINUE READING