Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior
@article{Haroon2012PsychoneuroimmunologyMN, title={Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior}, author={E. Haroon and C. Raison and A. Miller}, journal={Neuropsychopharmacology}, year={2012}, volume={37}, pages={137-162} }
The potential contribution of chronic inflammation to the development of neuropsychiatric disorders such as major depression has received increasing attention. Elevated biomarkers of inflammation, including inflammatory cytokines and acute-phase proteins, have been found in depressed patients, and administration of inflammatory stimuli has been associated with the development of depressive symptoms. Data also have demonstrated that inflammatory cytokines can interact with multiple pathways… CONTINUE READING
Figures, Tables, and Topics from this paper
Paper Mentions
577 Citations
Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications
- Psychology, Medicine
- Neuroscience
- 2013
- 520
CYTOKINE TARGETS IN THE BRAIN: IMPACT ON NEUROTRANSMITTERS AND NEUROCIRCUITS
- Psychology, Medicine
- Depression and anxiety
- 2013
- 418
- PDF
Imaging the Role of Inflammation in Mood and Anxiety-related Disorders
- Medicine
- Current neuropharmacology
- 2018
- 69
- PDF
The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implications.
- Medicine
- Current topics in behavioral neurosciences
- 2017
- 37
Neuroimmunological effects of physical exercise in depression
- Biology, Medicine
- Brain, Behavior, and Immunity
- 2012
- 124
Role of inflammation in depression: implications for phenomenology, pathophysiology and treatment.
- Medicine
- Modern trends in pharmacopsychiatry
- 2013
- 63
The role of depression and neuroimmune axis in the prognosis of cancer patients.
- Medicine
- Journal of B.U.ON. : official journal of the Balkan Union of Oncology
- 2014
- 7
Neurobiology and Therapeutic Potential of Cyclooxygenase-2 (COX-2) Inhibitors for Inflammation in Neuropsychiatric Disorders
- Medicine
- Front. Psychiatry
- 2019
- 12
- PDF
Anti-cytokine agents for anhedonia: targeting inflammation and the immune system to treat dimensional disturbances in depression
- Medicine
- Therapeutic advances in psychopharmacology
- 2018
- 20
References
SHOWING 1-10 OF 331 REFERENCES
Mechanisms of cytokine-induced behavioral changes: Psychoneuroimmunology at the translational interface
- Psychology, Medicine
- Brain, Behavior, and Immunity
- 2009
- 167
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
- Psychology, Medicine
- Biological Psychiatry
- 2009
- 2,439
- PDF
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders
- Psychology, Medicine
- Progress in Neurobiology
- 2008
- 258
Depressive disorders and immunity: 20 years of progress and discovery
- Medicine
- Brain, Behavior, and Immunity
- 2007
- 551
- PDF
Chronic immune stimulation correlates with reduced phenylalanine turnover.
- Biology, Medicine
- Current drug metabolism
- 2008
- 166
- Highly Influential
Angiotensin II AT1 Receptor Blockade Ameliorates Brain Inflammation
- Medicine
- Neuropsychopharmacology
- 2011
- 151
- PDF
Stress, food, and inflammation: psychoneuroimmunology and nutrition at the cutting edge.
- Medicine
- Psychosomatic medicine
- 2010
- 177
- PDF
TNFα Signaling in Depression and Anxiety: Behavioral Consequences of Individual Receptor Targeting
- Psychology, Medicine
- Biological Psychiatry
- 2006
- 220
Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
- Biology, Medicine
- Brain, Behavior, and Immunity
- 2007
- 482
- PDF
Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response
- Psychology, Medicine
- Molecular Psychiatry
- 2008
- 227
- PDF