Psychomotor effects of ketorolac in comparison with buprenorphine and diclofenac.

@article{Macdonald1989PsychomotorEO,
  title={Psychomotor effects of ketorolac in comparison with buprenorphine and diclofenac.},
  author={F C Macdonald and K. John Gough and Roger A Nicoll and Robert J. F. Dow},
  journal={British journal of clinical pharmacology},
  year={1989},
  volume={27 4},
  pages={453-9}
}
1. Ketorolac is an investigational non-opioid analgesic. Buprenorphine, an opioid compound and diclofenac, a non-steroidal anti-inflammatory, are analgesics used in clinical practise. 2. The psychomotor effects of ketorolac (30 mg), buprenorphine (0.3 mg), diclofenac (50 mg) and placebo all administered i.m., were examined in 12 healthy male volunteers (age 19-38 years), up to 8 h post-dose. 3. Creatine phosphokinase (CPK) was measured up to 24 h post-dose, providing an indication of local… CONTINUE READING