Psychomotor, executive, and memory function in preclinical Huntington's disease.

@article{Snowden2002PsychomotorEA,
  title={Psychomotor, executive, and memory function in preclinical Huntington's disease.},
  author={Julie S. Snowden and David Craufurd and James C. Thompson and David Neary},
  journal={Journal of clinical and experimental neuropsychology},
  year={2002},
  volume={24 2},
  pages={133-45}
}
The earliest changes in the development of Huntington's disease (HD) remain controversial. Studies of cognitive function in preclinical individuals who have the HD mutation have yielded contradictory results. This study compared cognitive and motor performance in 51 people with the HD mutation who had no clinical signs of HD, 85 at-risk individuals without the HD mutation and 43 individuals in the early stages of HD. Whereas highly significant differences were detected between the preclinical… CONTINUE READING