Psychological stress increased corticotropin-releasing hormone mRNA and content in the central nucleus of the amygdala but not in the hypothalamic paraventricular nucleus in the rat.

@article{Makino1999PsychologicalSI,
  title={Psychological stress increased corticotropin-releasing hormone mRNA and content in the central nucleus of the amygdala but not in the hypothalamic paraventricular nucleus in the rat.},
  author={Shinya Makino and Tamotsu Shibasaki and Naoko Yamauchi and Tatsuya Nishioka and T Mimoto and Ichiji Wakabayashi and Philip W. Gold and Kenji Hashimoto},
  journal={Brain research},
  year={1999},
  volume={850 1-2},
  pages={136-43}
}
The central administration of corticotropin-releasing hormone (CRH) to experimental animals sets into motion a coordinated series of physiological and behavioral events that promote survival during threatening situation. A large body of evidence suggest that CRH in the central nucleus of the amygdala (CEA) induces fear-related behaviors and is essential to fear conditioning; however, evidence of CRH-mediated activation of the amygdala under physiological situation is still limited. We report… CONTINUE READING