Psychological stress and disease.

  title={Psychological stress and disease.},
  author={Sheldon Cohen and Denise Janicki-Deverts and Gregory E. Miller},
  volume={298 14},
DESPITE WIDESPREAD PUBLIC BELIEF THAT PSYCHOlogical stress leads to disease, the biomedical community remains skeptical of this conclusion. In this Commentary, we discuss the plausibility of the belief that stress contributes to a variety of disease processes and summarize the role of stress in 4 major diseases: clinical depression, cardiovascular disease (CVD), human immunodeficiency virus (HIV)/AIDS, and cancer. 

Mindfulness-Based Stress Reduction and Diabetes

This review highlights the literature and research on Mindfulness-Based Stress Reduction to improve the health and well-being of individuals with diabetes.

Psychological Stress and Heart Disease: Fact or Folklore?

Stress and Cancer Risk: The Possible Role of Work Stress

Despite widespread public belief that stress may lead to cancer, research on this relationship remains inconclusive. However, recent work points to the possibility that hostile naturalistic settings

Correlation between Illness and Psychological Stress in Health Assessments

The study points to the need to incorporate psychological stress as a possible etiological factor in various forms of illness and suggests that the topic should be part of the training of health professionals, with emphasis on multidisciplinarity and interbranch collaboration.

Modeling the Diffusion of Psychological Stress

This chapter presents a set of mathematical and computational models that can be used to approach the modeling of psychological stress diffusion.

Psychological Disorders in Heart Failure.


This study regarding the Inter-relationship between stress, Waist Circumference and Blood pressure is done by using Ambulatory Blood Pressure Monitoring in medical professionals in this institute to create awareness amongst the medical fraternity.

A Stage Model of Stress and Disease

In this article, we argued that the term stress has served as a valuable heuristic, helping researchers to integrate traditions that illuminate different stages of the process linking stressful life



Stress, the Brain and Depression

Stress, the Brain and Depression gives evidence for how personality features, genetic factors, and psychosocial factors influence the interplay between stress and depression.

Effects of psychological and social factors on organic disease: a critical assessment of research on coronary heart disease.

It is suggested that, taken as a whole, evidence for a psychological and social impact on CAD morbidity and mortality is convincing, and continued progress in this area requires multidisciplinary research integrating expertise in cardiology and the behavioral sciences, and more effective efforts to communicate research findings to a biomedical audience.

Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy.

Suggestions to improve the assessment of behavioral interventions include more complete delineation of the physiological mechanisms by which such interventions might work; increased use of new, more convenient "alternative" end points for behavioral intervention trials; development of specifically targeted behavioral interventions (based on profiling of patient factors); and evaluation of previously developed models of predicting behavioral change.

Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology.

It is argued that distress-related immune dysregulation may be one core mechanism behind a large and diverse set of health risks associated with negative emotions, and resources such as close personal relationships that diminish negative emotions enhance health in part through their positive impact on immune and endocrine regulation.

Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry.

The present report meta-analyzes more than 300 empirical articles describing a relationship between psychological stress and parameters of the immune system in human participants to find that physical vulnerability as a function of age or disease also increased vulnerability to immune change during stressors.

Life Stressors as Risk Factors in Depression

Compelling evidence for an association between major adverse life experience and subsequent major depression is reviewed. Determining individual vulnerability to life stress and the effect of

Protective and damaging effects of stress mediators.

  • B. McEwen
  • Psychology
    The New England journal of medicine
  • 1998
The long-term effect of the physiologic response to stress is reviewed, which I refer to as allostatic load, which is the ability to achieve stability through change.

Stress and depression.

  • C. Hammen
  • Psychology
    Annual review of clinical psychology
  • 2005
There is growing interest in moving away from unidirectional models of the stress-depression association, toward recognition of the effects of contexts and personal characteristics on the occurrence of stressors, and on the likelihood of progressive and dynamic relationships between stress and depression over time.

The influence of bio-behavioural factors on tumour biology: pathways and mechanisms

This review integrates clinical, cellular and molecular studies to provide a mechanistic understanding of the interface between biological and behavioural influences in cancer, and identifies novel behavioural or pharmacological interventions that might help improve cancer outcomes.

Diathesis-stress theories in the context of life stress research: implications for the depressive disorders.

Advances in the conceptualization and measurement of life stress in the past 2 decades raise several questions concerning traditional diathesis-stress theories of psychopathology, and information is available on diatheses and stress for specific disorders to provide a foundation for more empirically based hypotheses about diathetic-stress interactions.