Psychological effects of ketamine in healthy volunteers. Phenomenological study.

  title={Psychological effects of ketamine in healthy volunteers. Phenomenological study.},
  author={Edith Pomarol-Clotet and Garry D. Honey and Graham K. Murray and Philip Corlett and Anthony R Absalom and Michael Lee and P. Joseph McKenna and Edward T. Bullmore and Paul C. Fletcher},
  journal={The British journal of psychiatry : the journal of mental science},
BACKGROUND The psychosis-inducing effect of ketamine is important evidence supporting the glutamate hypothesis of schizophrenia. However, the symptoms the drug produces have not been described systematically. AIM To examine the effects of ketamine in healthy people using a structured psychiatric interview. METHOD Ketamine (200 ng/ml) or placebo was administered by continuous infusion to 15 healthy volunteers. Symptoms were rated using the Present State Examination, the Thought, Language and… CONTINUE READING
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