• Psychology
• Published 2015

Psychological Well-Being and the Human Conserved Transcriptional Response to

@inproceedings{Fredrickson2015PsychologicalWA,
  title={Psychological Well-Being and the Human Conserved Transcriptional Response to},
  author={Barbara L. Fredrickson and Karen M Grewen and Sara B Algoe and Ann M. Firestine and Jeffrey Ma and Steve W. Cole},
  year={2015}
}

• Barbara L. Fredrickson, Karen M Grewen, +3 authors Steve W. Cole

Research in human social genomics has identified a conserved transcriptional response to adversity (CTRA) characterized by up-regulated expression of pro-inflammatory genes and down-regulated expression of Type I interferon- and antibody-related genes. This report seeks to identify the specific aspects of positive psychological well-being that oppose such effects and predict reduced CTRA gene expression. In a new confirmation study of 122 healthy adults that replicated the approach of a… CONTINUE READING

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