Psychogenic polydipsia review: Etiology, differential, and treatment

@article{Dundas2007PsychogenicPR,
  title={Psychogenic polydipsia review: Etiology, differential, and treatment},
  author={B. Dundas and M Harris and Meera Narasimhan},
  journal={Current Psychiatry Reports},
  year={2007},
  volume={9},
  pages={236-241}
}
Psychogenic polydipsia (PPD), a clinical disorder characterized by polyuria and polydipsia, is a common occurrence in inpatients with psychiatric disorders. The underlying pathophysiology of this syndrome is unclear, and multiple factors have been implicated, including a hypothalamic defect and adverse medication effects. Hyponatremia in PPD can progress to water intoxication and is characterized by symptoms of confusion, lethargy, and psychosis, and seizures or death. Evaluation of psychiatric… 
View on Springer
ncbi.nlm.nih.gov
119 Citations
Highly Influential Citations
8
Background Citations
41
Results Citations
1

119 Citations

Citation Type

Citation Type

Recognizing and Managing Pyschogenic Polydipsia in Mental Health
Psychogenic polydipsia: a mini review with three case-reports
TLDR
It is shown that PPD is associated with reduced life-expectancy in patients with schizophrenia, independently from psychiatric diagnosis, because of the many, and often serious, clinical complications.
Management of psychogenic polydipsia and hyponatremia in an acute mental health unit
TLDR
This case highlights the difficulties of managing psychogenic polydipsia in patients who are acutely unwell with low levels of insight and shows that even mild to moderate hyponatremia may be sufficient to trigger seizures in a patient with an underlying seizure disorder who is also on antipsychotic medication.
A rare cause of acute hyponatremia: Psychogenic polydipsia
TLDR
Hyponatremia patients may apply to emergency room with nonspecific symptoms such as nausea and vomiting at the onset and consciousness changes that may progress to coma and should be considered in patients with similar clinical findings and psychiatric history admitted to the emergency room.
A 27-Month-Old Boy with Polyuria and Polydipsia
TLDR
A 27-month-old boy who presented with polyuria and polydipsia is presented, highlighting the importance of water deprivation testing to differentiate between causes of polyuria, thereby avoiding misdiagnosis and iatrogenic hyponatremia.
Psychogenic Polydipsia with Hyponatraemia : A Case Report
TLDR
A 62 year old male patient who was admitted with impaired consciousness had been drinking more than 10 litres of water per day for four days and was diagnosed with psychogenic polydipsia with hyponatraemia.
Psychogenic Polydipsia With Hyponatremia: A Case Report
TLDR
A 62 year old male patient who was admitted with impaired consciousness had been drinking more than 10 litres of water per day for four days and was diagnosed with psychogenic polydipsia with hyponatraemia.
Psychogenic Polydipsia Complicated to Hyponatremia Induced Seizure in Schizophrenia: A Case Report from Nepal
TLDR
A case from Nepal is reported where psychogenic polydipsia was complicated to hyponatremia and lead to seizure episodes and it is emphasized on asking a routine question about polyDipsia in every patient of Schizophrenia in clinics.
Primary polydipsia in the medical and psychiatric patients
TLDR
This MD-PhD thesis aims at contributing to improving the pathophysiological understanding of, to characterize complications in, and to find treatment options for patients with primary polydipsia by evaluating glucagon-like peptide-1 receptor agonists, medications used to treat type 2 diabetes mellitus and obesity, as a treatment option.
Psychogenic Polydipsia – Management Challenges
TLDR
A 35-year old adult who was diagnosed with psychogenic polydipsia and was successfully managed with a combination of pharmacotherapy, fluid restriction and psychosocial management is presented.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 39 REFERENCES
Polydipsia and hyponatremia in psychiatric patients.
TLDR
Evaluation of psychiatric patients with polydipsia includes a search for other medical causes of polyd dipsia, polyuria, hyponatremia, and SIADH, and treatment modalities currently available include fluid restriction and medications.
Problems and progress in the diagnosis and treatment of polydipsia and hyponatremia.
TLDR
Case reports and open studies have shown that clozapine improves both polydipsia and water retention, but the response occurs at low doses and is not related to improvement in psychosis.
Differential effects of neuroleptic and clozapine on polydipsia and intermittent hyponatremia.
TLDR
If results of preliminary trials is substantiated, clozapine treatment may provide an opportunity to correct methodological problems and provide greater insight into the syndrome of polydipsia and intermittent hyponatremia.
Behavioral and Medical Treatment of Chronic Polydipsia in a Patient With Schizophrenia and Diabetes Insipidus
TLDR
The outpatient behavioral intervention demonstrated promising outcomes in a chronically mentally ill patient whose polydipsia had underlying psychogenic and physiological components and highlights the efficacy of combining behavioral and medical interventions.
Hyponatremia in psychogenic polydipsia.
TLDR
Twenty psychotic patients with psychogenic polydipsia had hyponatremia lasting up to 28 months, with headache, hypertension, dementia, seizures, lethargy, and coma, thus suggesting a "reset osmostat" or antidiuretic hormone response to nonosmotic stimuli.
Rhabdomyolysis after Correction of Hyponatremia Due to Psychogenic Polydipsia Possibly Complicated by Clozapine
TLDR
Hyponatremia due to water intoxication and concurrent use of clozapine should be considered in the differential diagnosis of rhabdomyolysis, especially in the severely psychiatrically disabled population.
Polydipsia in Chronic Psychiatric Patients: Therapeutic Trials of Clonidine and Enalapril
A double blind, placebo-controlled trial of demeclocycline treatment of polydipsia-hyponatremia in chronically psychotic patients
Epidemiology, pathophysiology, and management of hyponatremic encephalopathy.
Diuretic-Induced Hyponatremia
  • A. Spital
  • Medicine
    American Journal of Nephrology
  • 1999
TLDR
The pathogenesis, clinical features, prevention, and treatment of diuretic-induced hyponatremia are discussed in the hope that increased awareness and understanding will reduce the incidence and complications of this potentially life-threatening syndrome.
...
1
2
3
4
...