Psychobiotics: a novel class of psychotropic.

  title={Psychobiotics: a novel class of psychotropic.},
  author={Timothy G Dinan and Catherine Stanton and John F Cryan},
  journal={Biological psychiatry},
  volume={74 10},
Here, we define a psychobiotic as a live organism that, when ingested in adequate amounts, produces a health benefit in patients suffering from psychiatric illness. As a class of probiotic, these bacteria are capable of producing and delivering neuroactive substances such as gamma-aminobutyric acid and serotonin, which act on the brain-gut axis. Preclinical evaluation in rodents suggests that certain psychobiotics possess antidepressant or anxiolytic activity. Effects may be mediated via the… CONTINUE READING
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