Psychiatric disorders in preclinical Huntington's disease.

  title={Psychiatric disorders in preclinical Huntington's disease.},
  author={Camille L Julien and Jennifer C. Thompson and Sue Wild and Pamela Yardumian and Julie S. Snowden and Gwen Turner and David Craufurd},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={78 9},
BACKGROUND Psychiatric symptoms are a common feature of Huntington's disease (HD) and often precede the onset of motor and cognitive impairments. However, it remains unclear whether psychiatric changes in the preclinical period result from structural change, are a reaction to being at risk or simply a coincidental occurrence. Few studies have investigated the temporal course of psychiatric disorder across the preclinical period. OBJECTIVES To compare lifetime and current prevalence of… CONTINUE READING
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