Psychiatric and behavioural manifestations of Huntington ’ s disease


Huntington’s disease is an autosomal-dominant neurodegenerative disorder characterised by a triad of motor, cognitive and psychiatric symptoms (Box 1). It is the most common single-gene neurodegenerative disorder and has a prevalence of 4–10 per 100 000 of the population, with regional variations (Paulsen 2001). The psychiatric manifestations cause… (More)

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