Psychiatric adverse events during vigabatrin therapy.

  title={Psychiatric adverse events during vigabatrin therapy.},
  author={Douglas F. Levinson and Orrin Devinsky},
  volume={53 7},
OBJECTIVE To determine the incidence of psychiatric adverse events associated with vigabatrin therapy, we reviewed data from US and non-US double-blind, placebo-controlled trials of vigabatrin as add-on therapy for treatment-refractory partial epilepsy. METHODS "Verbatim" terms from investigators' reports had been translated into standard "preferred" terms using an adverse event dictionary. Terms for psychiatric events were then combined into categories for analysis of rates during vigabatrin… CONTINUE READING
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