Psychedelics in the treatment of unipolar mood disorders: a systematic review

  title={Psychedelics in the treatment of unipolar mood disorders: a systematic review},
  author={James J. H. Rucker and Luke A. Jelen and Sarah A Flynn and Kyle D Frowde and Allan H. Young},
  journal={Journal of Psychopharmacology},
  pages={1220 - 1229}
Unipolar mood disorders, including major depressive disorder and persistent depressive disorder (dysthymia), confer high rates of disability and mortality and a very high socioeconomic burden. Current treatment is suboptimal in most cases and there is little of note in the pharmaceutical development pipeline. The psychedelic drugs, including lysergic acid diethylamide and psilocybin, were used extensively in the treatment of mood disorders, and other psychiatric conditions, before their… 

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