Psychedelics and the essential importance of context
@article{CarhartHarris2018PsychedelicsAT, title={Psychedelics and the essential importance of context}, author={R. Carhart-Harris and L. Roseman and E. Haijen and D. Erritzoe and R. Watts and I. Branchi and M. Kaelen}, journal={Journal of Psychopharmacology}, year={2018}, volume={32}, pages={725 - 731} }
Psychedelic drugs are making waves as modern trials support their therapeutic potential and various media continue to pique public interest. In this opinion piece, we draw attention to a long-recognised component of the psychedelic treatment model, namely ‘set’ and ‘setting’ – subsumed here under the umbrella term ‘context’. We highlight: (a) the pharmacological mechanisms of classic psychedelics (5-HT2A receptor agonism and associated plasticity) that we believe render their effects… CONTINUE READING
Paper Mentions
81 Citations
Long-term effects of psychedelic drugs: A systematic review
- Psychology, Medicine
- Neuroscience & Biobehavioral Reviews
- 2020
- 6
Rethinking Therapeutic Strategies for Anorexia Nervosa: Insights From Psychedelic Medicine and Animal Models
- Medicine
- Frontiers in Neuroscience
- 2020
- 2
- PDF
Current perspectives on psychedelic therapy: use of serotonergic hallucinogens in clinical interventions
- Psychology, Medicine
- International review of psychiatry
- 2018
- 15
Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression
- Medicine
- Front. Pharmacol.
- 2018
- 101
- PDF
The psychedelic renaissance: the next trip for psychiatry?
- Psychology, Medicine
- Irish journal of psychological medicine
- 2019
- 1
- PDF
Post-acute psychological effects of classical serotonergic psychedelics: a systematic review and meta-analysis
- Medicine
- Psychological Medicine
- 2020
Are Psychedelics Something New in Teaching Psychopharmacology?
- Psychology, Medicine
- Academic Psychiatry
- 2020
- PDF
Serotonin, psychedelics and psychiatry
- Psychology, Medicine
- World psychiatry : official journal of the World Psychiatric Association
- 2018
- 11
Integrating psychotherapy and psychopharmacology: psychedelic-assisted psychotherapy and other combined treatments
- Medicine
- Expert review of clinical pharmacology
- 2020
- 1
References
SHOWING 1-10 OF 72 REFERENCES
The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future
- Psychology, Medicine
- Neuropsychopharmacology
- 2017
- 132
- PDF
Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression
- Medicine
- Front. Pharmacol.
- 2018
- 101
- PDF
The hidden therapist: evidence for a central role of music in psychedelic therapy
- Psychology, Medicine
- Psychopharmacology
- 2017
- 40
- PDF
Psychedelics in the treatment of unipolar mood disorders: a systematic review
- Psychology, Medicine
- Journal of psychopharmacology
- 2016
- 39
- PDF
Efficacy and Enlightenment: LSD Psychotherapy and the Drug Amendments of 1962
- Psychology, Medicine
- Journal of the history of medicine and allied sciences
- 2014
- 43
- PDF
Citalopram amplifies the influence of living conditions on mood in depressed patients enrolled in the STAR*D study
- Psychology, Medicine
- Translational Psychiatry
- 2017
- 19
- PDF
Psychedelics not linked to mental health problems or suicidal behavior: A population study
- Medicine
- Journal of psychopharmacology
- 2015
- 109
- PDF