Psychedelic Psychiatry’s Brave New World

@article{Nutt2020PsychedelicPB,
  title={Psychedelic Psychiatry’s Brave New World},
  author={David J. Nutt and David Erritzoe and Robin Lester Carhart-Harris},
  journal={Cell},
  year={2020},
  volume={181},
  pages={24-28}
}
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90 Citations
Highly Influential Citations
3
Background Citations
27
Results Citations
2

90 Citations

Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies
TLDR
Although the main focus was on efficacy and safety, study characteristics, duration of antidepressants effects across studies, and the role of the subjective drug experiences were also reviewed and presented.
Psychedelic drugs as new tools in psychiatric therapeutics
  • E. Schenberg
  • Psychology, Medicine
    Revista brasileira de psiquiatria
  • 2020
TLDR
The successful results of MDMA-assisted psychotherapy for Brazilian patients with severe PTSD are reported, and this approach deserves attention from mental health professionals nationwide, since the prevalence of this disorder, which is already high, is likely to increase as COVID-19 infections and fatalities escalate in Brazil.
Medicinal psychedelics for mental health and addiction: Advancing research of an emerging paradigm
TLDR
The sum of this research points towards medicinal psychedelics as a potential new class of psychiatric treatments when used within a medically supervised framework with integrated psychotherapeutic support, but before widespread translation into clinical use can occur, appropriately designed and sufficiently powered trials are required to detect both potential positive and negative outcomes.
From Psychiatry to Neurology: Psychedelics as Prospective Therapeutics for Neurodegenerative Disorders.
TLDR
Recent findings and information on how psychedelics may act therapeutically on cells within the central nervous system (CNS) during brain injuries and neurodegenerative diseases are discussed.
Psychedelic science in post-COVID-19 psychiatry
TLDR
Preliminary evidence from the rapidly progressing field of psychedelic science shows psilocybin therapy offers a promising transdiagnostic treatment strategy for a range of disorders with restricted and maladaptive habitual patterns of cognition and behaviour, notably depression, addiction and obsessive compulsive disorder.
Psychedelics as an emerging novel intervention in the treatment of substance use disorder: a review.
TLDR
The aim of this review is to examine the current standing of evidence regarding psychedelic psychopharmacology and to provide an overview of the use and effectiveness of these drugs in the treatment of SUD, alcohol use disorder, and for smoking cessation.
The Subjective Effects of Psychedelics May Not Be Necessary for Their Enduring Therapeutic Effects.
  • D. E. Olson
  • Psychology, Medicine
    ACS pharmacology & translational science
  • 2021
TLDR
Data is presented suggesting that the subjective effects induced by psychedelics may not be necessary to produce long-lasting changes in mood and behavior.
The promises and perils of psychedelic pharmacology for psychiatry.
TLDR
It is highlighted how basic science breakthroughs can guide the discovery and development of psychedelic-inspired medications with the potential for improved efficacy without hallucinogenic or rewarding actions.
The emerging role of psilocybin and MDMA in the treatment of mental illness
TLDR
Evaluate the therapeutic potential of traditional psychedelics, psilocybin, and MDMA, in the treatment of mental illness with a narrative review of available literature to indicate a single-dose, rapid effect model that have robust effects with treatment-resistant mental disorders and a unique advantage as a possible monotherapy for mental illness.
Perspective: Can psychedelic-assisted therapy be a promising aid in compulsive sexual behavior disorder treatment?
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