PsrA is a positive transcriptional regulator of the type III secretion system in Pseudomonas aeruginosa.

@article{Shen2006PsrAIA,
  title={PsrA is a positive transcriptional regulator of the type III secretion system in Pseudomonas aeruginosa.},
  author={D. K. Shen and Didier Filopon and Lauriane Kuhn and Benoit Polack and Bertrand Toussaint},
  journal={Infection and immunity},
  year={2006},
  volume={74 2},
  pages={1121-9}
}
The type III secretion system (TTSS) of Pseudomonas aeruginosa is induced in vivo upon contact with eukaryotic cells and in vitro by calcium depletion in culture medium. We have observed a previously identified protein, PsrA, necessary for full activation of TTSS gene expression in P. aeruginosa. Electrophoretic mobility shift assays showed that recombinant PsrA could bind to the exsCEBA promoter region. A mutant with a deletion in the psrA gene was constructed. Using transcriptional fusions… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…