Psoriatic patients with arthropathy show significant expression of free HLA class I heavy chains on circulating monocytes: a potential role in the pathogenesis of psoriatic arthropathy.

@article{Lan2004PsoriaticPW,
  title={Psoriatic patients with arthropathy show significant expression of free HLA class I heavy chains on circulating monocytes: a potential role in the pathogenesis of psoriatic arthropathy.},
  author={C C E Lan and Wen Chan Tsai and Chien-Sheng Wu and C. Yu and H. Yu},
  journal={The British journal of dermatology},
  year={2004},
  volume={151 1},
  pages={24-31}
}
BACKGROUND Surface free heavy chains on monocytes were recently implicated in playing a role in the pathogenesis of several forms of arthritis. OBJECTIVES To determine the expression of surface free heavy chains (recognized by monoclonal antibody HC10) on peripheral blood mononuclear cells of psoriatic patients with or without arthropathy. METHODS Twenty-eight psoriatic patients from the dermatology outpatient clinic were included in this study. Blood samples were collected during… CONTINUE READING