Psoriatic keratinocytes express high levels of nerve growth factor.

@article{Raychaudhuri1998PsoriaticKE,
  title={Psoriatic keratinocytes express high levels of nerve growth factor.},
  author={Smriti Kundu Raychaudhuri and William Y. Jiang and Eugene M. Farber},
  journal={Acta dermato-venereologica},
  year={1998},
  volume={78 2},
  pages={84-6}
}
Many investigators have reported proliferation of terminal cutaneous nerves and upregulation of various neuropeptides (substance P, vasoactive intestinal polypeptide, calcitonin gene-related peptide) in psoriatic lesions. Nerve growth factor promotes growth of nerves and causes upregulation of neuropeptides like substance P and calcitonin gene-related… CONTINUE READING