Psoriasis

@article{Boehncke2015Psoriasis,
  title={Psoriasis},
  author={W. H. Boehncke and Michael P. Sch{\"o}n},
  journal={The Lancet},
  year={2015},
  volume={386},
  pages={983-994}
}
Bacterial Dysbiosis and Translocation in Psoriasis Vulgaris
TLDR
Dysbiosis of the skin and gut microbiota may contribute to psoriasis, by promoting the translocation of microbes from these sites into the bloodstream, consistent with the Iron Dysregulation and Dormant Microbes hypothesis.
Serum peptides as putative modulators of inflammation in psoriasis.
MiR-217 is down-regulated in psoriasis and promotes keratinocyte differentiation via targeting GRHL2.
Shaping the spectrum - From autoinflammation to autoimmunity.
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  • 2016
Autophagy and Skin Diseases
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The new line of evidence suggests that autophagy is inextricably linked to skin disorders and is implicated in the pathophysiology of a variety of human diseases.
CB2R Deficiency Exacerbates Imiquimod-Induced Psoriasiform Dermatitis and Itch Through the Neuro-Immune Pathway
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It is demonstrated that CB2R plays a pivotal role in the pathophysiology of psoriasis, providing a new potential target for anti-inflammatory and antipruritic drugs.
Causal Biological Network Model for Inflammasome Signaling Applied for Interpreting Transcriptomic Changes in Various Inflammatory States
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This work assembled the available literature information on inflammasome activation into the CBN model and scored it with publicly available transcriptomic datasets that address viral infection of the lungs, osteo- and rheumatoid arthritis, psoriasis, and aging, demonstrating that theCBN model provides a platform for interpreting transcriptomic data in the context of inflammaome activation.
Chemistry, pharmacokinetics, pharmacological activities, and toxicity of Quercitrin
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The underlying molecular mechanisms of quercitrin in treating related diseases, the dose‐effect relationships, and the novel preparations were discussed on the purpose of broadening the application prospect of quERCitrin as functional food and providing reference for its clinical application.
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