Psoriasis, the liver, and the gastrointestinal tract.

  title={Psoriasis, the liver, and the gastrointestinal tract.},
  author={Paolo Gisondi and Micol del Giglio and Alessandra Cozzi and Giampiero Girolomoni},
  journal={Dermatologic therapy},
  volume={23 2},
Psoriasis is a common chronic inflammatory, immune-mediated skin disease that is frequently associated with comorbidities including psoriatic arthropathy, chronic inflammatory bowel diseases, and cardio-metabolic disorders. In particular, nonalcoholic fatty liver disease affects about half of patients, Crohn's disease 0.5% and celiac disease 0.2-4.3% of patients with psoriasis. Some shared genetic traits as well as common inflammatory pathways may underlie these associations. The presence of… CONTINUE READING
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