Psoriasin (S100A7), an antimicrobial peptide, is increased in human middle ear cholesteatoma.

@article{Kim2009PsoriasinA,
  title={Psoriasin (S100A7), an antimicrobial peptide, is increased in human middle ear cholesteatoma.},
  author={Ki Hyung Kim and Jae-Gu Cho and Jae-Jun Song and J Woo and Heung-Man Lee and Hak Hyun Jung and Soon-Jae Hwang and Sungwon Chae},
  journal={Acta oto-laryngologica},
  year={2009},
  volume={129 10},
  pages={1067-71}
}
CONCLUSION Increased psoriasin in cholesteatoma epithelium may play a role in epithelial inflammatory response and differentiation. OBJECTIVES Cholesteatoma is characterized by excessive keratinocyte differentiation leading to inflammation, granulation tissue, and osteolytic activity. Moreover, psoriasin may act as an antimicrobial peptide, stimulate granulocytes, and control keratinocyte differentiation. The purpose of this study was to investigate the differential expression patterns and… CONTINUE READING