Psilocybin: Psychotherapy or drug?

@article{Goodwin2016PsilocybinPO,
  title={Psilocybin: Psychotherapy or drug?},
  author={Guy M. Goodwin},
  journal={Journal of Psychopharmacology},
  year={2016},
  volume={30},
  pages={1201 - 1202}
}
  • G. Goodwin
  • Published 30 November 2016
  • Psychology
  • Journal of Psychopharmacology
This edition of the Journal of Psychopharmacology highlights two very similarly designed studies of the effects of the serotonergic agonist psilocybin on the psychological distress of cancer patients. In each case, the study was a cross-over design which compared, respectively, low-dose/high-dose psilocybin and niacin (placebo)/high-dose psilocybin. The results were very comparable, and suggest a clinically important effect: a single high dose of psilocybin reduced symptoms of anxiety and… 
The Utility of Psilocybin in Managing Anxiety and Depression in Cancer Patients
TLDR
Research on psilocybin will not only fuel more investigations into the therapeutic potential of other psychedelics, they will also spearhead more comprehensive treatment pathways for cancer patients.
Psychedelics and the essential importance of context
TLDR
This article highlights the pharmacological mechanisms of classic psychedelics that it is believed render their effects exceptionally sensitive to context, and develops an evidence base for long-held assumptions about the critical importance of context in relation to psychedelic use that can help minimise harms and maximise potential benefits.
Psychedelic revival: a mixed-methods analysis of recreational magic mushroom (psilocybin) use for transformational, micro-dosing and leisure purposes
Background: Following years of inactivity, psychedelic research has rapidly expanded within clinical and therapeutic fields. In particular, magic mushrooms (psilocybin), a plant-based psychedelic,
Pharmacies as potential providers of harm reduction services: A preliminary online survey
TLDR
The data suggest that the university-educated participants are supportive of treating recreational drug use as a health issue with GPs, mental health workers and pharmacists taking on roles.
The bad expert
TLDR
It is shown that a key mechanism in the construction of expertise cultures is the use of antithesis performances, which are performances of scientific and professional credibility that rely on telling stories about a scientific enemy or ostracized Other.

References

SHOWING 1-9 OF 9 REFERENCES
Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies
TLDR
The results suggest that the administration of moderate doses of psilocybin to healthy, high-functioning and well-prepared subjects in the context of a carefully monitored research environment is associated with an acceptable level of risk.
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial
TLDR
High-dose psilocybin produced large decreases in clinician- and self-rated measures of depressed mood and anxiety, along with increases in quality of life, life meaning, and optimism, and decreases in death anxiety.
Psychedelics and Mental Health: A Population Study
TLDR
It was found that in several cases psychedelic use was associated with lower rate of mental health problems, and use of psychedelics was not found to be an independent risk factor formental health problems.
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial
TLDR
Psilocybin was associated with enduring anxiolytic and anti-depressant effects in patients with cancer-related psychological distress, sustained benefits in existential distress and quality of life, as well as improved attitudes towards death.
Psychological treatments: A call for mental-health science
TLDR
It is fervently hoped that the government and concerned agencies will devote their energies to scaling up full immunization efforts in these displaced and marginal populations, rather than diverting resources to international travellers.
Structure and function of serotonin G protein-coupled receptors.
How serotonin shapes moral judgment and behavior
TLDR
A process model is presented whereby serotonin influences social behavior by shifting social preferences in the positive direction, enhancing the value people place on others’ outcomes.
A call for mentalhealth science
  • Nature
  • 2014
2016) Psilocybin produces substantial and sustained decrease in depression and anxiety in patients with life-threatening cancer: a randomized double-blind trial
  • J Psychopharmacol
  • 2016