Psilocybin, ein psychotroper Wirkstoff aus dem mexikanischen RauschpilzPsilocybe mexicana Heim

  title={Psilocybin, ein psychotroper Wirkstoff aus dem mexikanischen RauschpilzPsilocybe mexicana Heim},
  author={A. A. Hofmann and Roger Heim and A. Brack and H. R. Kobel},
The active principle ofPsilocybe mexicana Heim, a mexican mushroom with hallucinogenic properties, has been isolated in crystalline form. The compound has been given the namePsilocybin; it possesses indole characteristics and contains phosphorus. A second substance, closely related toPsilocybin but found only in traces, has been calledPsilocin. 
Observations on psychoneurophysiologically significant mushrooms
One of these compounds could be shown to possess the same chromophore as psilocybin, a 4-oxygenated indole system, and seems most likely to be the active compound of the mushroom.
Zur Pharmakologie von Psilocybin, einem Wirkstoff ausPsilocybe mexicana Heim
The active principle ofPsilocybe mexicana Heim, Psilocybin, is without marked effects on the isolated organs but exerts an actionin vivo which resembles a slight sympathetic stimulation.
The in vitro inhibitory effect of psilocybin and related compounds on human cholinesterases
There is no correlation between the in vitro anticholinesterase activity and the hallucinogenic effect of psilocybin, bufotenin and 5-hydroxytryptamine in human plasma, red cells and gray matter homogenate.
Psychoactive tryptamines from basidiomycetes
The biosynthesis and production of some tryptamines by the mycelial culture ofPsilocybe bohemicaŠebek is described, and a survey of methods for their analysis and isolation is conducted.
Fungal Hallucinogens Psilocin, Ibotenic Acid, and Muscimol: Analytical Methods and Biologic Activities
The present article offers an opportunity to find out what are the main symptoms of intoxication with mushrooms containing psilocybin/psilocin, muscimol, and ibotenic acid.
Identifizierung von Psilocin
Psilocin, a by-product of Psilocybin which is the active principle of hallucinogenic mushrooms, has been identified as 4-hydroxy-dimethyltryptamine.
Metabolism of psilocybin and psilocin: clinical and forensic toxicological relevance
This review aims to discuss metabolism of psilocybin and psilocin, by presenting all major and minor psychoactive metabolites, with clinical and forensic relevance in diagnosis.
Action de la Psilocybine sur le cerveau du lapin
Psilocybin, the by-product of which ‘Psilocin] has been identified as 4-hydroxy-dimethyl-tryptamine (4-HTP) develops in the waking rabbit a marked activation of the somatic behaviour and of the
Production Options for Psilocybin: Making of the Magic.
It is highlighted that the prospect of psilocybin as a promising therapeutic may entail an increased demand, which can be met by biotechnological production, and the concurrently developed concept of enzymatic in’vitro and heterologous in vivo production, along with previous synthetic routes.
Occurrence and use of hallucinogenic mushrooms containing psilocybin alkaloids
Although psilocybin-containing mushrooms are not what Nordic mushroom pickers are trying to find as food or food supplement, there is a risk, admittedly small, that these mushrooms accidentally will be collected and this may be a legal problem in some Nordic countries.