Pseudoxanthoma elasticum: high calcium intake in early life correlates with severity.

@article{Renie1984PseudoxanthomaEH,
  title={Pseudoxanthoma elasticum: high calcium intake in early life correlates with severity.},
  author={W A Renie and Reed Edwin Pyeritz and John W. Combs and Stuart L. Fine},
  journal={American journal of medical genetics},
  year={1984},
  volume={19 2},
  pages={235-44}
}
The characteristic histopathologic lesion of pseudoxanthoma elasticum (PXE) is calcification of the central core of elastic fibers in affected organs; it is correlated with clinical severity. One hypothesis holds that lowering dietary calcium might reduce or prevent tissue injury and minimize clinical effects. This hypothesis would be supported by demonstrating that clinical expression is positively associated with previous calcium intake. We studied 32 unrelated PXE patients (20 men and 12… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Dystrophic calcinosis cutis in pseudoxanthoma elasticum.

Journal of the American Academy of Dermatology • 2008
View 4 Excerpts
Highly Influenced

Pseudoxanthoma elasticum.

Handbook of clinical neurology • 2015
View 1 Excerpt

[Angioid streaks].

Journal francais d'ophtalmologie • 2012

Similar Papers

Loading similar papers…