Pseudomonas siderophores in the sputum of patients with cystic fibrosis

@article{Martin2011PseudomonasSI,
  title={Pseudomonas siderophores in the sputum of patients with cystic fibrosis},
  author={L. Martin and D. Reid and K. Sharples and I. Lamont},
  journal={BioMetals},
  year={2011},
  volume={24},
  pages={1059-1067}
}
The lungs of patients with cystic fibrosis become chronically infected with the bacterium Pseudomonas aeruginosa, which heralds progressive lung damage and a decline in health. Iron is a crucial micronutrient for bacteria and its acquisition is a key factor in infection. P. aeruginosa can acquire this element by secreting pyoverdine and pyochelin, iron-chelating compounds (siderophores) that scavenge iron and deliver it to the bacteria. Siderophore-mediated iron uptake is generally considered a… Expand
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