Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses and in vitro in vivo [ version 1 ; referees : awaiting peer review ]

@inproceedings{Dickinson2017PseudomonasEO,
  title={Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses and in vitro in vivo [ version 1 ; referees : awaiting peer review ]},
  author={Rebecca S. Dickinson and Fiona J. Murphy and Catherine H Doherty and Sam Williams and Ananda S. Mirchandani and Joseph Willson and John S. Scotti and Gail F Preston and Christopher J. Schofield and Moira K. B. Whyte and Sarah R Walmsley},
  year={2017}
}
Pseudomonas species are adapted to evade innate immune responses Background: and can persist at sites of relative tissue hypoxia, including the mucus-plugged airways of patients with cystic fibrosis and bronchiectasis. The ability of these bacteria to directly sense and respond to changes in local oxygen availability is in part consequent upon expression of the 2-oxoglutarate oxygenase, prolyl Pseudomonas hydroxylase (PPHD), which acts on elongation factor Tu (EF-Tu), and is homologous with the… CONTINUE READING