Pseudomonas aeruginosa rugose small-colony variants have adaptations that likely promote persistence in the cystic fibrosis lung.

@article{Starkey2009PseudomonasAR,
  title={Pseudomonas aeruginosa rugose small-colony variants have adaptations that likely promote persistence in the cystic fibrosis lung.},
  author={Melissa Starkey and Jason H Hickman and Luyan Ma and Niu Zhang and Susan K De Long and A. Hinz and Sergio Palacios and Colin S Manoil and Mary Jo Kirisits and Timothy D. Starner and Daniel J Wozniak and Caroline S Harwood and Matthew R. Parsek},
  journal={Journal of bacteriology},
  year={2009},
  volume={191 11},
  pages={3492-503}
}
Pseudomonas aeruginosa is recognized for its ability to colonize diverse habitats, ranging from soil to immunocompromised people. The formation of surface-associated communities called biofilms is one factor thought to enhance colonization and persistence in these diverse environments. Another factor is the ability of P. aeruginosa to diversify genetically, generating phenotypically distinct subpopulations. One manifestation of diversification is the appearance of colony morphology variants on… CONTINUE READING
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