Pseudomonas aeruginosa infection of zebrafish involves both host and pathogen determinants.

@article{Clatworthy2009PseudomonasAI,
  title={Pseudomonas aeruginosa infection of zebrafish involves both host and pathogen determinants.},
  author={Anne E. Clatworthy and Jenny See-Wai Lee and Mark Leibman and Zachary Kostun and Alan J Davidson and Deborah T Hung},
  journal={Infection and immunity},
  year={2009},
  volume={77 4},
  pages={
          1293-303
        }
}
Zebrafish (Danio rerio) have a number of strengths as a host model for infection, including genetic tractability, a vertebrate immune system similar to that of mammals, ease and scale of laboratory handling, which allows analysis with reasonable throughput, and transparency, which facilitates visualization of the infection. With these advantages in mind, we examined whether zebrafish could be used to study Pseudomonas aeruginosa pathogenesis and found that infection of zebrafish embryos with… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 72 CITATIONS, ESTIMATED 69% COVERAGE

The sensor kinase KinB regulates virulence in acute Pseudomonas aeruginosa infection.

  • Journal of bacteriology
  • 2011
VIEW 5 EXCERPTS
CITES RESULTS, METHODS & BACKGROUND

Host-Pathogen Interactions Made Transparent with the Zebrafish Model

  • Current drug targets
  • 2011
VIEW 6 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Infectious disease modeling and innate immune function in zebrafish embryos.

  • Methods in cell biology
  • 2011
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2009
2019

CITATION STATISTICS

  • 6 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 52 REFERENCES

A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Zebrafish-based small molecule discovery.

  • Chemistry & biology
  • 2003
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL