Pseudomonas aeruginosa exotoxin A: its role in retardation of wound healing: the 1992 Lindberg Award.

@article{Heggers1992PseudomonasAE,
  title={Pseudomonas aeruginosa exotoxin A: its role in retardation of wound healing: the 1992 Lindberg Award.},
  author={John P. Heggers and Scott Haydon and Francis Man Fung Ko and Peter G. Hayward and Stefan A. Carp and Martin C. Robson},
  journal={The Journal of burn care & rehabilitation},
  year={1992},
  volume={13 5},
  pages={
          512-8
        }
}
Bacterial concentrations greater than 10(5) colony-forming units/gm of tissue prevent wound healing. However, it has not been determined whether it is the number of bacteria or a toxin produced by these organisms that impedes the wound healing process. Pseudomonas aeruginosa (PSAR), a burn wound pathogen, produces a dermonecrotic toxin, exotoxin A. Studies have indicated a role for exotoxin A in the pathogenicity of PSAR. We investigated the role of exotoxin A in the retardation of contraction… CONTINUE READING
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