Pseudomonas aeruginosa biofilms in cystic fibrosis.

@article{Hiby2010PseudomonasAB,
  title={Pseudomonas aeruginosa biofilms in cystic fibrosis.},
  author={N. H{\o}iby and O. Ciofu and T. Bjarnsholt},
  journal={Future microbiology},
  year={2010},
  volume={5 11},
  pages={
          1663-74
        }
}
The persistence of chronic Pseudomonas aeruginosa lung infections in cystic fibrosis (CF) patients is due to biofilm-growing mucoid (alginate-producing) strains. A biofilm is a structured consortium of bacteria, embedded in a self-produced polymer matrix consisting of polysaccharide, protein and DNA. In CF lungs, the polysaccharide alginate is the major part of the P. aeruginosa biofilm matrix. Bacterial biofilms cause chronic infections because they show increased tolerance to antibiotics and… Expand
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