Pseudomonas aeruginosa adherence to remodelling respiratory epithelium.

  title={Pseudomonas aeruginosa adherence to remodelling respiratory epithelium.},
  author={Sophie de Bentzmann and P. Roger and Edith Puchelle},
  journal={The European respiratory journal},
  volume={9 10},
Pseudomonas aeruginosa is an opportunistic organism, which frequently colonizes the respiratory tract of patients with impaired host defence. In cystic fibrosis (CF) patients, this pathogen causes a progressive destructive bronchitis and bronchiolitis and is responsible for high mortality. Normal respiratory epithelium is protected against bacteria via mucus and mucociliary clearance. Alteration of mucociliary clearance and of glycosylation of mucins in CF facilitates the access of bacteria to… CONTINUE READING
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