Pseudomonas aeruginosa adherence to external auditory canal epithelium.

@article{Sundstrm1997PseudomonasAA,
  title={Pseudomonas aeruginosa adherence to external auditory canal epithelium.},
  author={J Sundstr{\"o}m and C Agrup and G{\"o}ran Kronvall and Bengt Wretlind},
  journal={Archives of otolaryngology--head \& neck surgery},
  year={1997},
  volume={123 12},
  pages={
          1287-92
        }
}
BACKGROUND Pseudomonas aeruginosa is an important causative agent for external otitis. The specific bacterium-host reaction has not been investigated. It is therefore unknown whether adhesion of the external otitis strain to the external auditory canal epithelium is increased compared with strains isolated from other infections. DESIGN A cohort study was designed to outline adhesion of P aeruginosa to the external auditory canal epithelium, cultured in vitro, of the guinea pig. Factors… Expand
Quantity of aerobic bacteria in the bony portion of the external auditory canal of children.
TLDR
The purpose of this study was to quantify the bacteria normally harboured in the healthy EAC and on a well-defined region of the cavum conchae of children. Expand
External otitis caused by infection with Pseudomonas aeruginosa or Candida albicans cured by use of a topical group III steroid, without any antibiotics
Conclusions Irrespective of the microbial agent, group III steroid solution cured external otitis efficiently in a rat model. The addition of antibiotic components to steroid solutions for theExpand
Otopathogenic Pseudomonas aeruginosa strains as competent biofilm formers.
TLDR
Strains of OPPA isolated from cholesteatoma are strongly adherent to keratinocytes and capable of forming biofilm, and OPPA strains have mucoid characteristics in vitro, suggesting that OPPA can contribute to biofilm formation in cholESTeatoma, leading to the persistence of this infection. Expand
Transcription Levels of Pseudomonas aeruginosa Exotoxin A Gene and Severity of Symptoms in Patients with Otitis Externa
TLDR
Polymerase chain reaction (PCR)-based detection and transcription of the gene encoding a potent virulence factor, the exotoxin A, were done on 32 isolates of Pseudomonas aeruginosa belonging to 23 genotypes, and all isolates with the exception of two had the exOToxin A transcription demonstrated by the production of a 396-bp amplicon from RT-PCR-amplified RNA. Expand
[Problem of increasing resistance of pseudomonas aeruginosa in patients at ENT Clinic of Poznan University of Medical Sciences in the years 2005-2007].
TLDR
Overuse of cotrimoxazol, doxycyclin and cefuroxim in empiric treatment, Pseudomonas aeruginosa strains are naturally resistant to which, is responsible for the resistance to most commonly used antibiotics. Expand
Problematyka narastania oporności Pseudomonas aeruginosa u pacjentów hospitalizowanych w Klinice Otolaryngologii i Onkologii Laryngologicznej Uniwersytetu Medycznego w Poznaniu w latach 2005–2007
TLDR
Overuse of cotrimoxazol, doxycyclin and cefuroxim in empiric treatment, Pseudomonas aeruginosa strains are naturally resistant to which, is responsible for the P. aerug inosa resistance to most commonly used antibiotics. Expand
Elastase Deficiency Phenotype of Pseudomonas aeruginosa Canine Otitis Externa Isolates
TLDR
Pseudomonas aeruginosa veterinary isolates were assayed for elastase and total matrix protease activity and results indicate that canine ear isolates have a distinctElastase phenotype. Expand
Considerations on acute otitis externa for its optimized treatment
TLDR
Staging of otitis allows comparisons of the level of involvement and treatment recommendations: aspiration is advisable in stages II, III, and IV; placement of a wick inside the canal is necessary in stages III and IV. Expand
5. Microbiology and Immunology
TLDR
In viral respiratory infections, several studies have shown correlations between concentrations of acute-phase cytokines and chemokines in respiratory secretions and concentrations of virus in the nasopharynx, white blood cell counts, and severity of the disease. Expand
Externa Isolates Canine Otitis Pseudomonas aeruginosa Elastase Deficiency Phenotype of
TLDR
Two elastases (LasA and LasB) and analkaline protease (AprA) are well-characterized and often act syner-gistically to cleave connective tissues and immune system components. Expand
...
1
2
...

References

SHOWING 1-10 OF 22 REFERENCES
Pseudomonas aeruginosa in otitis externa. A particular variety of the bacteria?
TLDR
P aeruginosa in otitis externa displayed fewer of the usual biochemical features of the species than did the strains isolated from other infections, and produced less pyocyanin and less urease and exhibited no mucoid-producing strains. Expand
Microbial aetiology of otitis externa.
  • W. Dibb
  • Medicine
  • The Journal of infection
  • 1991
TLDR
Otitis externa involving Gram-positive bacteria seems to be more prevalent in this area than in that of other reported studies, and the finding of streptococci and S. aureus was rare whereas that of P. aeruginosa or absence of growth was common. Expand
Modulation of Pseudomonas aeruginosa adherence to the corneal surface by mucus
TLDR
The mucus layer, and, in particular, the mucin fraction of mucus, modulated adherence to intact corneal epithelium of Pseudomonas aeruginosa but not that of Staphylococcus aureus or Streptococcus pyogenes. Expand
Role of mechanical injury on airway surface in the pathogenesis of Pseudomonas aeruginosa.
TLDR
The results suggest that brush injury on tracheal surface produces new binding sites as a receptor for P. aeruginosa, and that this receptor has carbohydrates as important components and that it is not a protein receptor. Expand
Malignant external otitis: review and personal experience.
TLDR
An extensive review of the literature and personal experience concludes that imaging has great diagnostic relevance: CT and MRI are very useful for spatial resolution, while radionuclide scanning and SPECT are superior for detecting early osteitis and monitoring response to therapy. Expand
Chronische Otitis externa aus dermatologischer Sicht
TLDR
Examination should include functional assessment of the Eustachian tube and middle ear and allergy testing (patch, prick test), Preparations for local therapy should contain a limited number of constituents and avoid common allergens. Expand
Immunologic investigations of mucoid strains of Pseudomonas aeruginosa: comparison of susceptibility to opsonic antibody in mucoid and nonmucoid strains.
TLDR
A mucoid strain not requiring antibody for opsonization was shown to use primarily the alternative complement pathway, consistent with the hypothesis that the immunodeterminant for o Simpsonic antibody in nonmucoid strains is blocked in the mucoids. Expand
The relationship of phenotype changes in Pseudomonas aeruginosa to the clinical condition of patients with cystic fibrosis.
TLDR
The majority of strains of P. aeruginosa isolated from CF patients with chronic bronchopulmonary infection had 3 distinctive features, loss of 0 serotype reaction, expression of a new somatic antigen, and sensitivity to normal human serum. Expand
Genetic analysis of Pseudomonas aeruginosa adherence: distinct genetic loci control attachment to epithelial cells and mucins
TLDR
Findings suggest that P. aeruginosa can express at least two adhesins distinct from pili, one recognizing receptors shared by epithelial cells and mucins and the other recognizing mucins alone. Expand
Pseudomonas aeruginosa enzyme profiling: predictor of potential invasiveness and use as an epidemiological tool
TLDR
A comparison of the enzyme profiles of the environmental andclinical isolates indicated that colonization or infection by environmental strains of P. aeruginosa is a rare event and that environmental and clinical strains comprise separate biovars. Expand
...
1
2
3
...