Pseudomonas aeruginosa Uses Multiple Pathways To Acquire Iron during Chronic Infection in Cystic Fibrosis Lungs

@article{Konings2013PseudomonasAU,
  title={Pseudomonas aeruginosa Uses Multiple Pathways To Acquire Iron during Chronic Infection in Cystic Fibrosis Lungs},
  author={Anna F Konings and Lois W. Martin and Katrina Sharples and Louise F Roddam and Roger D Latham and David W. Reid and Iain L. Lamont},
  journal={Infection and Immunity},
  year={2013},
  volume={81},
  pages={2697 - 2704}
}
ABSTRACT Pseudomonas aeruginosa chronically infects the lungs of more than 80% of adult patients with cystic fibrosis (CF) and is a major contributor to the progression of disease pathology. P. aeruginosa requires iron for growth and has multiple iron uptake systems that have been studied in bacteria grown in laboratory culture. The purpose of this research was to determine which of these are active during infection in CF. RNA was extracted from 149 sputum samples obtained from 23 CF patients… Expand
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