Pseudomonas aeruginosa-Candida albicans interactions: localization and fungal toxicity of a phenazine derivative.

@article{Gibson2009PseudomonasAA,
  title={Pseudomonas aeruginosa-Candida albicans interactions: localization and fungal toxicity of a phenazine derivative.},
  author={Jane Gibson and Arpana Sood and Deborah A. Hogan},
  journal={Applied and environmental microbiology},
  year={2009},
  volume={75 2},
  pages={504-13}
}
Phenazines are redox-active small molecules that play significant roles in the interactions between pseudomonads and diverse eukaryotes, including fungi. When Pseudomonas aeruginosa and Candida albicans were cocultured on solid medium, a red pigmentation developed that was dependent on P. aeruginosa phenazine biosynthetic genes. Through a genetic screen in combination with biochemical experiments, it was found that a P. aeruginosa-produced precursor to pyocyanin, proposed to be 5-methyl… CONTINUE READING
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