Pseudohypoxia induced by miR-126 deactivation promotes migration and therapeutic resistance in renal cell carcinoma.

Abstract

Pseudohypoxia plays a central role in the progression and therapeutic resistance of clear cell renal cell carcinoma (ccRCC); however, the underlying mechanisms are poorly understood. MicroRNA miR-126 has decreased expression in metastatic or relapsed ccRCC as compared to primary tumors, but the mechanisms by which miR-126 is implicated in RCC remain unknown… (More)
DOI: 10.1016/j.canlet.2017.02.025

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Cite this paper

@article{Liu2017PseudohypoxiaIB, title={Pseudohypoxia induced by miR-126 deactivation promotes migration and therapeutic resistance in renal cell carcinoma.}, author={Weijun Liu and Hanxiang Chen and Nathan Wong and W. John Haynes and Callie M. Baker and Xiaowei Wang}, journal={Cancer letters}, year={2017}, volume={394}, pages={65-75} }