Pseudogenes: are they "junk" or functional DNA?

@article{Balakirev2003PseudogenesAT,
  title={Pseudogenes: are they "junk" or functional DNA?},
  author={E. Balakirev and F. Ayala},
  journal={Annual review of genetics},
  year={2003},
  volume={37},
  pages={
          123-51
        }
}
Pseudogenes have been defined as nonfunctional sequences of genomic DNA originally derived from functional genes. It is therefore assumed that all pseudogene mutations are selectively neutral and have equal probability to become fixed in the population. Rather, pseudogenes that have been suitably investigated often exhibit functional roles, such as gene expression, gene regulation, generation of genetic (antibody, antigenic, and other) diversity. Pseudogenes are involved in gene conversion or… Expand
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