Pseudoaffective cardioautonomic responses to gastric distension in rats.

  title={Pseudoaffective cardioautonomic responses to gastric distension in rats.},
  author={Gervais Tougas and Lu Wang},
  journal={The American journal of physiology},
  volume={277 1 Pt 2},
We examined the heart rate response to gastric distension, the involvement of vagal and sympathetic sensory afferents, adrenergic and cholinergic neural pathways, and the effects of capsaicin on this response in anesthetized rats. Gastric distension volume dependently decreased heart rate by 24.5% (resting rate = 219.87 ± 14.06 beats/min, mean rate during gastric distension with 15 ml = 165.97 ± 17.36 beats/min, P < 0.05). The bradycardic response was significantly decreased after removal of… CONTINUE READING