Pseudo five-component synthesis of 2,5-di(hetero)arylthiophenes via a one-pot Sonogashira–Glaser cyclization sequence

Abstract

Based upon a consecutive one-pot Sonogashira-Glaser coupling-cyclization sequence a variety of 2,5-di(hetero)arylthiophenes were synthesized in moderate to good yields. A single Pd/Cu-catalyst system, without further catalyst addition, and easily available, stable starting materials were used, resulting in a concise and highly efficient route for the… (More)
DOI: 10.3762/bjoc.7.174

Topics

Cite this paper

@inproceedings{Urselmann2011PseudoFS, title={Pseudo five-component synthesis of 2,5-di(hetero)arylthiophenes via a one-pot Sonogashira–Glaser cyclization sequence}, author={Dominik Urselmann and Dragutin Antovic and Thomas J. Mueller}, booktitle={Beilstein journal of organic chemistry}, year={2011} }