Prx1 and Prx2 cooperatively regulate the morphogenesis of the medial region of the mandibular process.


Mice lacking both Prx1 and Prx2 display severe abnormalities in the mandible. Our analysis showed that complete loss of Prx gene products leads to growth abnormalities in the mandibular processes evident as early as embryonic day (E) 10.5 associated with changes in the survival of the mesenchyme in the medial region. Changes in the gene expression in the… (More)
DOI: 10.1002/dvdy.22092