Pruritus and mast cell proliferation in the skin of haemodialysis patients

@article{Szepietowski1995PruritusAM,
  title={Pruritus and mast cell proliferation in the skin of haemodialysis patients},
  author={Jacek C Szepietowski and Theophilus Thepen and Willem A. van Vloten and Tomasz Szepietowski and Ilse C Bihari},
  journal={Inflammation Research},
  year={1995},
  volume={44},
  pages={S84-S85}
}
Uremic pruritus is one of the most disturbing symptoms in patients with end-stage renal failure, affecting 60% to 65% of haemodialysis patients [1, 2]. Although several theories have been suggested, the etiopathogenesis of uremic pruritus remains unclear. Because dermal mast cells are regarded as one of the main sources of histamine and elevated levels of plasma histamine are found in uremic patients [2], this study was undertaken to evaluate mast cell proliferation in the skin of patients… CONTINUE READING

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