• Corpus ID: 35589965

Pruritus: a review.

@article{Weisshaar2003PruritusAR,
  title={Pruritus: a review.},
  author={Elke Weisshaar and Michael J Kucenic and Alan B. Fleischer},
  journal={Acta dermato-venereologica. Supplementum},
  year={2003},
  volume={213},
  pages={
          5-32
        }
}
The history, neurophysiology, clinical aspects and treatment of pruritus are reviewed in this article. The different forms of pruritus in dermatological and systemic diseases are described, and the various aetiologies and pathophysiology of pruritus in systemic diseases are discussed. Lack of understanding of the neurophysiology and pathophysiology of pruritus has hampered the development of adequate therapies. Nevertheless, the discovery of primary afferent neurons and, presumably, second… 

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Intractable chronic pruritus in a 67-year-old man.

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References

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This review highlights the recent knowledge of different mechanisms which may be involved in regulating pruritus in patients with AD potentially leading to new therapeutic applications for the treatment of itch in AD.

Uremic pruritus: A review

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Inflammation and malnutrition are recognized risk factors for cardiovascular death in end‐stage renal disease patients, which may be related to the genesis of pruritus.

Paroxetine in a Case of Psychogenic Pruritus and Neurotic Excoriations

Pruritus can be the presenting symptom of a serious organic disease in absence of other clinical and laboratory abnormalities, and it is indispensable to reevaluate periodically any patient with persistent pruritus.

The Pathophysiological Puzzle of Uremic Pruritus — Insights and Speculations from Therapeutic and Epidemiological Studies

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Uremic pruritus remains a frequent and sometimes tormenting problem in patients with advanced or end-stage renal insufficiency and the exact pathophysiology of UP is unknown, and systematically performed studies are lacking and hard to obtain.

Treatment of prurigo nodularis with topical capsaicin.

Topical treatment of prurigo nodularis with capsaicin with a concentration- and regimen-ranging study proved to be an effective and safe regimen resulting in clearing of the skin lesions.

Uremic Pruritus – An Update

Uremic pruritus is the itch manifesting in patients with chronic renal insufficiency, and new ideas about immunologic mechanisms are seen in recent articles, emphasizing the role of T-helper (Th) type 1 lymphocytes and interleukin (IL)-2.

Uraemic pruritus--new perspectives and insights from recent trials.

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Uraemic pruritus remains a frequent and sometimes tormenting problem in patients with advanced or end-stage renal disease and, given the great clinical heterogenicity of UP, systematically performed studies are hard to obtain and are therefore sparse.

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Uremic pruritus. Clinical and experimental studies.

The results suggest that the accumulation of pruritogens between dialysis sessions influences the intensity of itching, and suggests that hemodialysis patients develop an abnormal pattern of cutaneous innervation.

Treatment of PUVA itch with capsaicin

Six patients with PUVA itch were treated with capsaicin cream and five patients experienced a dramatic improvement within 48 h and complete resolution in a mean of h days (range 2-14), while the sixth patient had generalized itch, developed a severe burning sensation and treatment was discontinued.
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