Pruning genome-scale metabolic models to consistent ad functionem networks.

@article{Hoffmann2007PruningGM,
  title={Pruning genome-scale metabolic models to consistent ad functionem networks.},
  author={Sabrina Hoffmann and Andreas Hoppe and Hermann-Georg Holzh{\"u}tter},
  journal={Genome informatics. International Conference on Genome Informatics},
  year={2007},
  volume={18},
  pages={308-19}
}
Metabolic networks represent a set of reactions and associated metabolites that may occur in a given cell or tissue. They are frequently reconstructed from pure genomic data without thorough biochemical validation. Such genome-scale metabolic networks may thus either lack relevant or contain non-existent reactions and metabolites. Filling gaps and removing… CONTINUE READING