Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts.

@article{Zdailov2009PrunellaVE,
  title={Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts.},
  author={Ad{\'e}la Zdařilov{\'a} and Alena Rajnochov{\'a} Svobodov{\'a} and Vil{\'i}m {\vS}im{\'a}nek and Jitka Ulrichov{\'a}},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2009},
  volume={23 3},
  pages={386-92}
}
Periodontitis is a chronic disease associated with inflammation of the tooth-supporting tissues. The inflammation is initiated by a group of gram-negative anaerobic bacteria. These express a number of irritating factors including a lipopolysaccharide (LPS), which plays a key role in periodontal disease development. Plant extracts with anti-inflammatory and anti-microbial properties have been shown to inhibit bacterial plaque formation and thus prevent chronic gingivitis. In this study we tested… CONTINUE READING
37 Citations
32 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 37 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 32 references

Similar Papers

Loading similar papers…