Prucalopride: A Review of Its Use in the Management of Chronic Constipation

@article{Keating2013PrucaloprideAR,
  title={Prucalopride: A Review of Its Use in the Management of Chronic Constipation},
  author={G. Keating},
  journal={Drugs},
  year={2013},
  volume={73},
  pages={1935-1950}
}
The highly selective serotonin 5-HT4 receptor agonist prucalopride (Resolor®, Resotran®, Resotrans®) is indicated for the treatment of chronic constipation. [...] Key Result In four randomized, double-blind, multicentre, 12-week trials in patients (predominantly women) with chronic constipation, oral prucalopride 2 mg once daily improved bowel function to a significantly greater extent than placebo, with a significantly greater proportion of prucalopride than placebo recipients achieving an average of ≥3…Expand
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