Pru p 3-Epitope-based sublingual immunotherapy in a murine model for the treatment of peach allergy.


SCOPE Food-specific immunotherapy (SIT) is a promising treatment for lipid transfer protein (LTP)-syndrome. We propose a novel sublingual-SIT (SLIT) that combines a Pru p 3 T-cell peptide and an oligodeoxyribonucleotide (ODN) with CpG motifs (ODN-CpG) as adjuvants to induce a specific Th1/Treg response. METHODS AND RESULTS LTP-peach allergic mice were… (More)
DOI: 10.1002/mnfr.201700110


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