Proxy assessment of quality of life in pediatric clinical trials: Application of the Health Utilities Index 3

@article{Cox2004ProxyAO,
  title={Proxy assessment of quality of life in pediatric clinical trials: Application of the Health Utilities Index 3},
  author={Cheryl L Cox and Shelly Lensing and Shesh N. Rai and Pam Hinds and Elizabeth A Burghen and Ching-Hon Pui},
  journal={Quality of Life Research},
  year={2004},
  volume={14},
  pages={1045-1056}
}
Background: With increased cure rates, pediatric oncology protocols increasingly seek to document the impact of treatment on patients’ disease, symptoms, and functional capacity. Procedure: Nurses as proxy respondents used the Health Utilities Index 3 (HUI3) to assess the health-related quality of life (HRQL) in twenty-five patients (age 6 years or older) enrolled on a frontline protocol for leukemia. HRQL observations (n = 70) were made at three different time points to coincide with high-dose… CONTINUE READING

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