Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases*♦

  title={Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases*♦},
  author={Marcus Gutscher and Mirko C. Sobotta and Guido H Wabnitz and Seda Ballikaya and Andreas J Meyer and Yvonne Samstag and Tobias P Dick},
  booktitle={The Journal of biological chemistry},
H(2)O(2) acts as a signaling molecule by oxidizing critical thiol groups on redox-regulated target proteins. To explain the efficiency and selectivity of H(2)O(2)-based signaling, it has been proposed that oxidation of target proteins may be facilitated by H(2)O(2)-scavenging peroxidases. Recently, a peroxidase-based protein oxidation relay has been identified in yeast, namely the oxidation of the transcription factor Yap1 by the peroxidase Orp1. It has remained unclear whether the protein… CONTINUE READING
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Redox Relay for Live Cell Imaging of H2O2 31540 JOURNAL OF BIOLOGICAL CHEMISTRY

  • C. Lee, S. M. Lee, +6 authors S. E. andRyu
  • Struct.Mol. Biol.11,
  • 2004

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