Proximal tubular metalloprotease activity is decreased in the senescent rat kidney.

Abstract

Proximal tubule brush border membrane-enriched fractions (BBM) from young (4 months) and old (20-22 months) male Sprague-Dawley rats were prepared by differential centrifugation and metalloprotease activity was measured using radioiodinated insulin B chain as substrate. Proteolytic activity is expressed as Units (U), where 1 U = 1 microgram insulin B chain… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.