Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration.

@article{Smeets2013ProximalTC,
  title={Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration.},
  author={Bart Smeets and Peter Boor and Henry B. P. M. Dijkman and Shagun V Sharma and Peggy Jirak and Fieke J M Mooren and Katja Berger and J{\"o}rg Bornemann and Irwin H. Gelman and Juergen Floege and Johan van der Vlag and Jack F. M. Wetzels and Marcus M{\"o}ller},
  journal={The Journal of pathology},
  year={2013},
  volume={229 5},
  pages={645-59}
}
Regeneration of injured tubular cells occurs after acute tubular necrosis primarily from intrinsic renal cells. This may occur from a pre-existing intratubular stem/progenitor cell population or from any surviving proximal tubular cell. In this study, we characterize a CD24-, CD133-, and vimentin-positive subpopulation of cells scattered throughout the proximal tubule in normal human kidney. Compared to adjacent 'normal' proximal tubular cells, these CD24-positive cells contained less cytoplasm… CONTINUE READING
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Repair of injured proximal tubule does not involve specialized progenitors.

Proceedings of the National Academy of Sciences of the United States of America • 2011

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